Papers.

• 2014 ESC/EACTS Guidelines on myocardial revascularization 4,211 citations
• FinnGen provides genetic insights from a well-phenotyped isolated population 4,210 citations
• Triple-Negative Breast Cancer 4,208 citations
• Where Is the Semantic System? A Critical Review and Meta-Analysis of 120 Functional Neuroimaging Studies 4,203 citations
• Evidence-Based Medicine 4,200 citations
• Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis 4,194 citations
• MetaboAnalyst 5.0: narrowing the gap between raw spectra and functional insights 4,191 citations
• The PRISMA 2020 statement: An updated guideline for reporting systematic reviews 4,186 citations
• AASLD guidelines for the treatment of hepatocellular carcinoma 4,185 citations
• Improved Survival with an Implanted Defibrillator in Patients with Coronary Disease at High Risk for Ventricular Arrhythmia 4,178 citations
• Artificial Intelligence (AI): Multidisciplinary perspectives on emerging challenges, opportunities, and agenda for research, practice and policy 4,178 citations
• The landscape of somatic copy-number alteration across human cancers 4,175 citations
• 2020 International Society of Hypertension Global Hypertension Practice Guidelines 4,162 citations
• The Patient Health Questionnaire Somatic, Anxiety, and Depressive Symptom Scales: a systematic review 4,159 citations
• Gut Microbiota in Health and Disease 4,150 citations
• Fourth Universal Definition of Myocardial Infarction (2018) 4,149 citations
• Environmental and Heritable Factors in the Causation of Cancer — Analyses of Cohorts of Twins from Sweden, Denmark, and Finland 4,148 citations
• Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial 4,139 citations
• A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. 4,130 citations
• Methods to detect, characterize, and remove motion artifact in resting state fMRI 4,129 citations
• Compendium of Physical Activities: classification of energy costs of human physical activities 4,122 citations
• Frailty Consensus: A Call to Action 4,122 citations
• Synthesis without meta-analysis (SWiM) in systematic reviews: reporting guideline 4,122 citations
• Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers 4,116 citations
• Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study 4,112 citations
• Depression, chronic diseases, and decrements in health: results from the World Health Surveys 4,104 citations
• Spin-Torque Switching with the Giant Spin Hall Effect of Tantalum 4,098 citations
• Estimating Glomerular Filtration Rate from Serum Creatinine and Cystatin C 4,098 citations
• Evaluating Online Labor Markets for Experimental Research: Amazon.com's Mechanical Turk 4,098 citations
• The global epidemiology of hypertension 4,096 citations
• Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: a systematic review and meta-analysis 4,096 citations
• The Role of Tumoral FOXP3 on Cell Proliferation, Migration, and Invasion in Gastric Cancer 4,095 citations
• Survey of Wireless Indoor Positioning Techniques and Systems 4,080 citations
• The 2011 Report on Dietary Reference Intakes for Calcium and Vitamin D from the Institute of Medicine: What Clinicians Need to Know 4,064 citations
• Dietary pattern analysis: a new direction in nutritional epidemiology 4,063 citations
• The Global Epidemic of the Metabolic Syndrome 4,063 citations
• Molecular characterization of mitochondrial apoptosis-inducing factor 4,059 citations
• Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease 4,056 citations
• Guidelines for the use and interpretation of assays for monitoring autophagy 4,056 citations
• Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses 4,052 citations
• Global Prevalence of Chronic Kidney Disease – A Systematic Review and Meta-Analysis 4,050 citations
• DRC: A dual route cascaded model of visual word recognition and reading aloud. 4,046 citations
• 2013 AHA/ACC/TOS Guideline for the Management of Overweight and Obesity in Adults 4,046 citations
• Comprehensive genomic characterization of squamous cell lung cancers 4,044 citations
• Comparison of Upper Gastrointestinal Toxicity of Rofecoxib and Naproxen in Patients with Rheumatoid Arthritis 4,044 citations
• Functional Characterization of the <i>S. cerevisiae</i> Genome by Gene Deletion and Parallel Analysis 4,040 citations
• WHO analysis of causes of maternal death: a systematic review 4,040 citations
• BAY 43-9006 Exhibits Broad Spectrum Oral Antitumor Activity and Targets the RAF/MEK/ERK Pathway and Receptor Tyrosine Kinases Involved in Tumor Progression and Angiogenesis 4,035 citations
• Proposed Modifications to the Duke Criteria for the Diagnosis of Infective Endocarditis 4,033 citations
• Annual Research Review: A meta‐analysis of the worldwide prevalence of mental disorders in children and adolescents 4,031 citations
• Screening and Prostate-Cancer Mortality in a Randomized European Study 4,027 citations
• Thermal runaway mechanism of lithium ion battery for electric vehicles: A review 4,023 citations
• The ATLAS Experiment at the CERN Large Hadron Collider 4,011 citations
• An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics 4,003 citations
• The Integrative Action of the Nervous System. 3,999 citations
• Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia 3,993 citations
• Measuring Health-Related Quality of Life 3,992 citations
• Long-Term Use of a Left Ventricular Assist Device for End-Stage Heart Failure 3,979 citations
• Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB) 3,976 citations
• Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10 801 women in 17 randomised trials 3,967 citations
• Heuristic Decision Making 3,966 citations
• Autophagy regulates lipid metabolism 3,959 citations
• Mindfulness-based stress reduction and health benefits 3,958 citations
• <i>EGFR</i> Mutation and Resistance of Non–Small-Cell Lung Cancer to Gefitinib 3,956 citations
• HOW CELLS RESPOND TO INTERFERONS 3,956 citations
• Movement‐Related effects in fMRI time‐series 3,954 citations
• Definition and classification of chronic kidney disease: A position statement from Kidney Disease: Improving Global Outcomes (KDIGO) 3,953 citations
• Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU 3,949 citations
• Opinion Paper: “So what if ChatGPT wrote it?” Multidisciplinary perspectives on opportunities, challenges and implications of generative conversational AI for research, practice and policy 3,939 citations
• Interventions for preventing falls in older people living in the community 3,938 citations
• Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) 3,934 citations
• <i>Gaia</i>Early Data Release 3 3,929 citations
• Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel 3,925 citations
• Heart Disease and Stroke Statistics—2009 Update 3,924 citations
• On the Self-Regulation of Behavior 3,919 citations
• What is cognitive reserve? Theory and research application of the reserve concept 3,913 citations
• 2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death 3,913 citations
• The FAB 3,909 citations
• NF-κB: a key role in inflammatory diseases 3,899 citations
• Clinical Targets for Continuous Glucose Monitoring Data Interpretation: Recommendations From the International Consensus on Time in Range 3,898 citations
• The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity 3,889 citations
• Serum TSH, T₄, and Thyroid Antibodies in the United States Population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III) 3,887 citations
• Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015 3,886 citations
• The science of fake news 3,885 citations
• Mild cognitive impairment 3,884 citations
• Tumour heterogeneity and resistance to cancer therapies 3,879 citations
• Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease 3,866 citations
• Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses 3,865 citations
• 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults 3,864 citations
• Guidelines for the diagnosis and treatment of pulmonary hypertension: The Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT) 3,863 citations
• Nomenclature of Systemic Vasculitides 3,855 citations
• Local-Global Parcellation of the Human Cerebral Cortex from Intrinsic Functional Connectivity MRI 3,854 citations
• Glycemic index of foods: a physiological basis for carbohydrate exchange 3,853 citations
• Medical Management of Hyperglycemia in Type 2 Diabetes: A Consensus Algorithm for the Initiation and Adjustment of Therapy 3,848 citations
• Race, Breast Cancer Subtypes, and Survival in the Carolina Breast Cancer Study 3,847 citations
• MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis 3,847 citations
• 2012 focused update of the ESC Guidelines for the management of atrial fibrillation 3,834 citations
• The size and burden of mental disorders and other disorders of the brain in Europe 2010 3,826 citations
• A distributed, developmental model of word recognition and naming. 3,818 citations
• Integrative Genomic Profiling of Human Prostate Cancer 3,815 citations
• Quantitative Insulin Sensitivity Check Index: A Simple, Accurate Method for Assessing Insulin Sensitivity In Humans 3,813 citations
• Molecular Spectra and Molecular Structure. I. Spectra of Diatomic Molecules 3,811 citations
• Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 3,808 citations
• Understanding plant responses to drought — from genes to the whole plant 3,805 citations
• Vascular Contributions to Cognitive Impairment and Dementia 3,803 citations
• The repertoire of mutational signatures in human cancer 3,802 citations
• No health without mental health 3,800 citations
• Vascular Endothelial Growth Factor in Ocular Fluid of Patients with Diabetic Retinopathy and Other Retinal Disorders 3,795 citations
• Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo-controlled trial 3,793 citations
• Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial—Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial 3,792 citations
• Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants 3,792 citations
• Prostaglandins and Inflammation 3,787 citations
• 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension 3,786 citations
• A Randomized Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Major Depression 3,782 citations
• Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC 3,781 citations
• Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine 3,780 citations
• Spatial registration and normalization of images 3,780 citations
• Effects of enalapril on mortality in severe congestive heart failure: Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS) 3,778 citations
• Our future: a Lancet commission on adolescent health and wellbeing 3,778 citations
• Mortality, morbidity, and risk factors in China and its provinces, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 3,778 citations
• The RCP greenhouse gas concentrations and their extensions from 1765 to 2300 3,777 citations
• Kidney Disease as a Risk Factor for Development of Cardiovascular Disease 3,773 citations
• Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis 3,773 citations
• Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden 3,771 citations
• Genomic analyses identify molecular subtypes of pancreatic cancer 3,769 citations
• Doing Research in the Real World 3,765 citations
• Statistical Methods For Assessing Measurement Error (Reliability) in Variables Relevant to Sports Medicine 3,758 citations
• European guidelines on cardiovascular disease prevention in clinical practice: executive summary: Fourth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (Constituted by representatives of nine societies and by invited experts) 3,758 citations
• Classification criteria for psoriatic arthritis: Development of new criteria from a large international study 3,755 citations
• Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects 3,749 citations
• Reduction of Maternal-Infant Transmission of Human Immunodeficiency Virus Type 1 with Zidovudine Treatment 3,748 citations
• Parkinson's disease 3,745 citations
• Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013 3,743 citations
• Fourth Universal Definition of Myocardial Infarction (2018) 3,743 citations
• Public and private self-consciousness: Assessment and theory. 3,742 citations
• Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial 3,735 citations
• Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline 3,734 citations
• ACC/AHA 2005 Practice Guidelines for the Management of Patients With Peripheral Arterial Disease (Lower Extremity, Renal, Mesenteric, and Abdominal Aortic) 3,723 citations
• 2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults 3,722 citations
• Age at onset of mental disorders worldwide: large-scale meta-analysis of 192 epidemiological studies 3,721 citations
• Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures 3,719 citations
• Perception of the speech code. 3,715 citations
• A global double‐fluorescent Cre reporter mouse 3,708 citations
• Biological, clinical and population relevance of 95 loci for blood lipids 3,705 citations
• 2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk 3,704 citations
• Fish Consumption, Fish Oil, Omega-3 Fatty Acids, and Cardiovascular Disease 3,703 citations
• Duodenal Infusion of Donor Feces for Recurrent <i>Clostridium difficile</i> 3,700 citations
• Docetaxel and Estramustine Compared with Mitoxantrone and Prednisone for Advanced Refractory Prostate Cancer 3,691 citations
• Integrative Clinical Genomics of Advanced Prostate Cancer 3,688 citations
• A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing 3,683 citations
• Pembrolizumab plus Chemotherapy for Squamous Non–Small-Cell Lung Cancer 3,676 citations
• A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial 3,671 citations
• Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. The Report of an American Academy of Sleep Medicine Task Force. 3,671 citations
• Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial 3,664 citations
• Empagliflozin and Progression of Kidney Disease in Type 2 Diabetes 3,655 citations
• Temsirolimus, Interferon Alfa, or Both for Advanced Renal-Cell Carcinoma 3,653 citations
• Effects of a Combination of Beta Carotene and Vitamin A on Lung Cancer and Cardiovascular Disease 3,650 citations
• Health inequalities among British civil servants: the Whitehall II study 3,647 citations
• Evolving concepts of rheumatoid arthritis 3,642 citations
• Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from <i>BRCA</i> Mutation Carriers 3,640 citations
• Transcatheter Aortic-Valve Replacement with a Self-Expanding Valve in Low-Risk Patients 3,636 citations
• Clinical Practice Guideline for Screening and Management of High Blood Pressure in Children and Adolescents 3,631 citations
• The development of QUADAS: a tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews 3,627 citations
• A standard procedure for creating a frailty index 3,621 citations
• Circulating Angiogenic Factors and the Risk of Preeclampsia 3,620 citations
• Enhancing transparency in reporting the synthesis of qualitative research: ENTREQ 3,619 citations
• Chronic Health Conditions in Adult Survivors of Childhood Cancer 3,617 citations
• A Bayesian Hierarchical Model for Learning Natural Scene Categories 3,617 citations
• Obesity and Cardiovascular Disease: A Scientific Statement From the American Heart Association 3,617 citations
• Alcohol use and burden for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 3,614 citations
• The Transcriptional Landscape of the Mammalian Genome 3,611 citations
• A Quantitative Assessment of Plasma Homocysteine as a Risk Factor for Vascular Disease 3,608 citations
• Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analyses? 3,608 citations
• Benefit of Carotid Endarterectomy in Patients with Symptomatic Moderate or Severe Stenosis 3,608 citations
• 2014 AHA/ACC Guideline for the Management of Patients With Non–ST-Elevation Acute Coronary Syndromes 3,607 citations
• Guidelines on the management of valvular heart disease: The Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology 3,595 citations
• Image inpainting 3,594 citations
• The global burden of hip and knee osteoarthritis: estimates from the Global Burden of Disease 2010 study 3,593 citations
• The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5 3,591 citations
• Single-pixel imaging via compressive sampling 3,584 citations
• Genotypic and Histological Evolution of Lung Cancers Acquiring Resistance to EGFR Inhibitors 3,582 citations
• OARSI guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis 3,579 citations
• Psychological correlates of university students' academic performance: A systematic review and meta-analysis. 3,578 citations
• Guidelines on the management of valvular heart disease (version 2012) 3,570 citations
• Recommendations for chamber quantification☆ 3,566 citations
• First-Line Atezolizumab plus Chemotherapy in Extensive-Stage Small-Cell Lung Cancer 3,565 citations
• The Lancet Commission on global mental health and sustainable development 3,564 citations
• Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome 3,564 citations
• Validity of the Executive Function Theory of Attention-Deficit/Hyperactivity Disorder: A Meta-Analytic Review 3,559 citations
• Deciding Advantageously Before Knowing the Advantageous Strategy 3,558 citations
• <i>LMO2</i> -Associated Clonal T Cell Proliferation in Two Patients after Gene Therapy for SCID-X1 3,556 citations
• Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients 3,556 citations
• A manifesto for reproducible science 3,553 citations
• ESC/EAS Guidelines for the management of dyslipidaemias: The Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS) 3,549 citations
• Isolation of rare circulating tumour cells in cancer patients by microchip technology 3,549 citations
• Global Disparities of Hypertension Prevalence and Control 3,544 citations
• CONSORT 2010 statement: extension to randomised pilot and feasibility trials 3,544 citations
• Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts 3,540 citations
• Acquired Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib Is Associated with a Second Mutation in the EGFR Kinase Domain 3,538 citations
• Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) 3,537 citations

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