Papers.

• The PRISMA 2020 statement: an updated guideline for reporting systematic reviews 100,010 citations
• Measuring inconsistency in meta-analyses 63,469 citations
• ImageNet: A large-scale hierarchical image database 62,405 citations
• Regression Shrinkage and Selection Via the Lasso 52,325 citations
• The PHQ-9 44,905 citations
• Consolidated criteria for reporting qualitative research (COREQ): a 32-item checklist for interviews and focus groups 42,723 citations
• ImageNet Large Scale Visual Recognition Challenge 40,426 citations
• An Introduction to the Bootstrap 39,875 citations
• The Cochrane Collaboration's tool for assessing risk of bias in randomised trials 34,575 citations
• A Brief Measure for Assessing Generalized Anxiety Disorder 32,089 citations
• RoB 2: a revised tool for assessing risk of bias in randomised trials 31,918 citations
• Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man 31,585 citations
• Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study 29,181 citations
• The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration 27,995 citations
• Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement 26,815 citations
• A New Equation to Estimate Glomerular Filtration Rate 25,894 citations
• Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2 24,563 citations
• The Elements of Statistical Learning 24,375 citations
• The Elements of Statistical Learning 23,937 citations
• A pneumonia outbreak associated with a new coronavirus of probable bat origin 23,394 citations
• GRADE: an emerging consensus on rating quality of evidence and strength of recommendations 22,655 citations
• The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: Guidelines for Reporting Observational Studies 21,902 citations
• A global reference for human genetic variation 20,256 citations
• An integrated encyclopedia of DNA elements in the human genome 19,593 citations
• Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 19,593 citations
• Corrigendum to: 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: Developed by the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) With the special contribution of the Heart Failure Association (HFA) of the ESC. 19,548 citations
• ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions 19,544 citations
• The Elements of Statistical Learning: Data Mining, Inference, and Prediction 19,412 citations
• The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies 19,386 citations
• Investigation of the freely available easy-to-use software ‘EZR’ for medical statistics 19,017 citations
• Recommendations for Cardiac Chamber Quantification by Echocardiography in Adults: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging 18,200 citations
• Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia 17,987 citations
• The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration 17,836 citations
• Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement 17,818 citations
• The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: Guidelines for Reporting Observational Studies 17,521 citations
• Regularization Paths for Generalized Linear Models via Coordinate Descent 17,408 citations
• A New Method for Measuring Daytime Sleepiness: The Epworth Sleepiness Scale 17,336 citations
• The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies 16,938 citations
• Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis 15,942 citations
• ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data 15,842 citations
• Adverse Renal Effects of Immune Checkpoint Inhibitors: A Narrative Review 15,290 citations
• A More Accurate Method To Estimate Glomerular Filtration Rate from Serum Creatinine: A New Prediction Equation 15,156 citations
• PhysioBank, PhysioToolkit, and PhysioNet 14,693 citations
• Robust enumeration of cell subsets from tissue expression profiles 14,324 citations
• Sarcopenia: revised European consensus on definition and diagnosis 14,320 citations
• Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010 14,309 citations
• Guidelines for the Process of Cross-Cultural Adaptation of Self-Report Measures 14,304 citations
• An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest 14,245 citations
• Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 14,166 citations
• The behaviour change wheel: A new method for characterising and designing behaviour change interventions 13,980 citations
• Optical Coherence Tomography 13,798 citations
• The PRISMA 2020 statement: an updated guideline for reporting systematic reviews 13,729 citations
• A Proportional Hazards Model for the Subdistribution of a Competing Risk 13,718 citations
• 2013 ESH/ESC Guidelines for the management of arterial hypertension 13,692 citations
• The Sequence of the Human Genome 13,684 citations
• UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age 13,641 citations
• Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 13,599 citations
• Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation 13,354 citations
• Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure 13,329 citations
• 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 13,317 citations
• Heart Disease and Stroke Statistics—2017 Update: A Report From the American Heart Association 12,771 citations
• Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer 12,730 citations
• 2013 ACCF/AHA Guideline for the Management of Heart Failure 12,638 citations
• Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding 12,597 citations
• Bioconductor: open software development for computational biology and bioinformatics 12,580 citations
• Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes 12,121 citations
• Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013 12,111 citations
• A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 12,015 citations
• The RAST Server: Rapid Annotations using Subsystems Technology 11,951 citations
• Diagnosis and Management of the Metabolic Syndrome 11,851 citations
• Sarcopenia: European consensus on definition and diagnosis 11,800 citations
• An Introduction to Statistical Learning 11,799 citations
• Should We STOP Angiotensin Converting Enzyme Inhibitors/Angiotensin Receptor Blockers in Advanced Kidney Disease? 11,736 citations
• The PRISMA 2020 statement: An updated guideline for reporting systematic reviews 11,706 citations
• K/DOQI clinical practice guidelines for chronic kidney disease: Evaluation, classification, and stratification 11,659 citations
• Aspirin plus Clopidogrel as Secondary Prevention after Stroke or Transient Ischemic Attack: A Systematic Review and Meta-Analysis 11,558 citations
• Use of Chemotherapy plus a Monoclonal Antibody against HER2 for Metastatic Breast Cancer That Overexpresses HER2 11,555 citations
• Cortical Surface-Based Analysis 11,549 citations
• Chronic Kidney Disease and the Risks of Death, Cardiovascular Events, and Hospitalization 11,409 citations
• World Health Organization 2020 guidelines on physical activity and sedentary behaviour 11,383 citations
• Using the framework method for the analysis of qualitative data in multi-disciplinary health research 11,369 citations
• Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019 11,363 citations
• Recommendations for Chamber Quantification: A Report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, Developed in Conjunction with the European Association of Echocardiography, a Branch of the European Society of Cardiology 11,362 citations
• PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews 11,353 citations
• Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines 11,331 citations
• Dabigatran versus Warfarin in Patients with Atrial Fibrillation 11,232 citations
• Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications 10,963 citations
• Fast, sensitive and accurate integration of single-cell data with Harmony 10,925 citations
• A novel potent vasoconstrictor peptide produced by vascular endothelial cells 10,806 citations
• Observation of a new particle in the search for the Standard Model Higgs boson with the ATLAS detector at the LHC 10,734 citations
• Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide 10,718 citations
• Food in the Anthropocene: the EAT–Lancet Commission on healthy diets from sustainable food systems 10,714 citations
• Significance analysis of microarrays applied to the ionizing radiation response 10,707 citations
• AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both 10,687 citations
• The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration 10,666 citations
• GRADE guidelines: 1. Introduction—GRADE evidence profiles and summary of findings tables 10,645 citations
• Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9th edition 10,642 citations
• Evaluation, Treatment, and Prevention of Vitamin D Deficiency: an Endocrine Society Clinical Practice Guideline 10,540 citations
• 2018 ESC/ESH Guidelines for the management of arterial hypertension 10,520 citations
• The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration 10,497 citations
• Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. 10,459 citations
• Dementia prevention, intervention, and care: 2020 report of the Lancet Commission 10,454 citations
• A typology of reviews: an analysis of 14 review types and associated methodologies 10,442 citations
• Strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies 10,407 citations
• The mutational constraint spectrum quantified from variation in 141,456 humans 10,295 citations
• The global distribution and burden of dengue 10,287 citations
• The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease 10,281 citations
• Signatures of mutational processes in human cancer 10,238 citations
• Pembrolizumab versus Chemotherapy for PD-L1–Positive Non–Small-Cell Lung Cancer 10,184 citations
• Statistical significance for genomewide studies 10,161 citations
• The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: Guidelines for reporting observational studies 10,071 citations
• Perceptual Losses for Real-Time Style Transfer and Super-Resolution 10,064 citations
• 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS) 10,035 citations
• IDF Diabetes Atlas: Global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045 10,005 citations
• Observation of a new boson at a mass of 125 GeV with the CMS experiment at the LHC 10,001 citations
• Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling 9,976 citations
• Adolescence-limited and life-course-persistent antisocial behavior: A developmental taxonomy. 9,906 citations
• MULTIVARIABLE PROGNOSTIC MODELS: ISSUES IN DEVELOPING MODELS, EVALUATING ASSUMPTIONS AND ADEQUACY, AND MEASURING AND REDUCING ERRORS 9,866 citations
• Statistical parametric maps in functional imaging: A general linear approach 9,835 citations
• 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation 9,826 citations
• Surviving Sepsis Campaign 9,750 citations
• Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 9,739 citations
• The Amber biomolecular simulation programs 9,682 citations
• Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls 9,682 citations
• Prediction of Coronary Heart Disease Using Risk Factor Categories 9,655 citations
• 2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative 9,640 citations
• Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray 9,611 citations
• The american college of rheumatology 1990 criteria for the classification of fibromyalgia 9,608 citations
• PD-1 Blockade in Tumors with Mismatch-Repair Deficiency 9,519 citations
• Nivolumab versus Docetaxel in Advanced Nonsquamous Non–Small-Cell Lung Cancer 9,504 citations
• From local explanations to global understanding with explainable AI for trees 9,466 citations
• Rivaroxaban versus Warfarin in Nonvalvular Atrial Fibrillation 9,441 citations
• <i>EGFR</i> Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy 9,435 citations
• Heart Disease and Stroke Statistics—2020 Update: A Report From the American Heart Association 9,424 citations
• Regression Modeling Strategies 9,312 citations
• Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease 9,298 citations
• Quantity and Quality of Exercise for Developing and Maintaining Cardiorespiratory, Musculoskeletal, and Neuromotor Fitness in Apparently Healthy Adults 9,225 citations
• Heart Disease and Stroke Statistics—2019 Update: A Report From the American Heart Association 9,170 citations
• The Effect of Spironolactone on Morbidity and Mortality in Patients with Severe Heart Failure 9,145 citations
• CONSORT 2010 Explanation and Elaboration: updated guidelines for reporting parallel group randomised trials 9,098 citations
• Whole Brain Segmentation 9,095 citations
• 2019 ESC/EAS Guidelines for the management of dyslipidaemias: <i>lipid modification to reduce cardiovascular risk</i> 9,055 citations
• Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 9,028 citations
• Apixaban versus Warfarin in Patients with Atrial Fibrillation 8,956 citations
• Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China 8,761 citations
• Isolation of Putative Progenitor Endothelial Cells for Angiogenesis 8,745 citations
• Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017 8,725 citations
• <i>Gaia</i> Data Release 2 8,703 citations
• Nivolumab versus Docetaxel in Advanced Squamous-Cell Non–Small-Cell Lung Cancer 8,599 citations
• The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity 8,591 citations
• Compendium of Physical Activities: an update of activity codes and MET intensities 8,570 citations
• European Guidelines on cardiovascular disease prevention in clinical practice (version 2012): The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts) * Developed with the special contribution of the European Association for Cardiovascular Prevention &amp; Rehabilitation (EACPR) 8,524 citations
• ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease 8,514 citations
• Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): Explanation and Elaboration 8,512 citations
• Grading quality of evidence and strength of recommendations 8,508 citations
• Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S) 8,491 citations
• Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 8,427 citations
• Recommendations for Cardiac Chamber Quantification by Echocardiography in Adults: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging 8,404 citations
• Construction of a genetic linkage map in man using restriction fragment length polymorphisms. 8,387 citations
• ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction—Executive Summary 8,377 citations
• Assessing coping strategies: A theoretically based approach. 8,368 citations
• Heart disease and stroke statistics--2015 update: a report from the American Heart Association. 8,341 citations
• The PRISMA Extension Statement for Reporting of Systematic Reviews Incorporating Network Meta-analyses of Health Care Interventions: Checklist and Explanations 8,331 citations
• 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation 8,328 citations
• GRADE guidelines: 3. Rating the quality of evidence 8,291 citations
• Gefitinib or Carboplatin–Paclitaxel in Pulmonary Adenocarcinoma 8,284 citations
• An integrated map of genetic variation from 1,092 human genomes 8,269 citations
• Integrated genomic analyses of ovarian carcinoma 8,204 citations
• Biological insights from 108 schizophrenia-associated genetic loci 8,164 citations
• Influence of Life Stress on Depression: Moderation by a Polymorphism in the 5-HTT Gene 8,146 citations
• The Behavior Change Technique Taxonomy (v1) of 93 Hierarchically Clustered Techniques: Building an International Consensus for the Reporting of Behavior Change Interventions 8,130 citations
• A map of human genome variation from population-scale sequencing 8,118 citations
• p53 Mutations in Human Cancers 8,115 citations
• SPIRIT 2013 Statement: Defining Standard Protocol Items for Clinical Trials 8,056 citations
• Dexamethasone in Hospitalized Patients with Covid-19. 8,046 citations
• Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer 8,040 citations
• 2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults 8,027 citations
• The representative concentration pathways: an overview 8,011 citations
• Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer 7,996 citations
• Power failure: why small sample size undermines the reliability of neuroscience 7,951 citations
• Closing the gap in a generation: health equity through action on the social determinants of health 7,944 citations
• Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study 7,931 citations
• Effects of Intensive Glucose Lowering in Type 2 Diabetes 7,920 citations
• Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion 7,915 citations
• Brain–computer interfaces for communication and control 7,899 citations
• Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 7,839 citations
• Comprehensive genomic characterization defines human glioblastoma genes and core pathways 7,837 citations
• Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes 7,831 citations
• Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015 7,819 citations
• KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease 7,800 citations
• 10-Year Follow-up of Intensive Glucose Control in Type 2 Diabetes 7,788 citations
• Biological effects of essential oils – A review 7,787 citations
• WHO Declares COVID-19 a Pandemic. 7,777 citations
• Global burden of hypertension: analysis of worldwide data 7,719 citations
• Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults 7,704 citations
• Movement Disorder Society‐sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS‐UPDRS): Scale presentation and clinimetric testing results 7,632 citations
• Dissociable Intrinsic Connectivity Networks for Salience Processing and Executive Control 7,592 citations
• Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials 7,572 citations
• MDS clinical diagnostic criteria for Parkinson's disease 7,559 citations
• General Cardiovascular Risk Profile for Use in Primary Care 7,541 citations

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