Amyotrophic Lateral Sclerosis Research

TopicLeading institutions, researchers & key papers

This cluster of papers focuses on the molecular mechanisms, genetics, and pathology of Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD). It covers topics such as TDP-43, FUS/TLS, C9ORF72 mutations, neurodegeneration of motor neurons, RNA processing, progranulin deficiency, ubiquitin-positive inclusions, and the genetic underpinnings of these diseases.

471

Works

IDs:OpenAlex

How has Amyotrophic Lateral Sclerosis Research's publication output changed over time?

ScholarIQpublication output · 2000–2019

Output grew0% over the shown period — from 1 works in 2000 to 1 in 2019.

2000200620082009201020112012201320172019

What are the most-cited papers on Amyotrophic Lateral Sclerosis Research?

ScholarIQmost cited works

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

D.R. Rosen, Teepu Siddique, David T. Patterson, Denise A. Figlewicz, Peter C. Sapp, Afif Hentati, Deirdre Donaldson, Jun Goto, J. O'Regan, Han‐Xiang Deng, Zohra Rahmani, Aldis Krizus, Diane McKenna‐Yasek, Annarueber Cayabyab, Sandra M. Gaston, Ralph Berger, Rudolph E. Tanzi, John Halperin, Brian Herzfeldt, R. van den Bergh, W.‐Y. Hung, Thomas D. Bird, Gang Deng, Donald W. Mulder, Celestine Smyth, Nigel G. Laing, Edwin Soriano, Margaret A. Pericak‐Vance, Jonathan Haines, Guy A. Rouleau, James S. Gusella, H. Robert Horvitz, Robert Brown

Nature. 19937,074 Citations

Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis

Manuela Neumann, Deepak M. Sampathu, Linda K. Kwong, Adam C. Truax, Matthew C. Micsenyi, Thomas T. Chou, Jennifer Bruce, Theresa Schuck, Murray Grossman, Christopher M. Clark, Leo McCluskey, Bruce L. Miller, Eliezer Masliah, Ian R. Mackenzie, Howard Feldman, W. Feiden, Hans A. Kretzschmar, John Q. Trojanowski, Virginia M.‐Y. Lee

Science. 20066,678 Citations

El Escorial revisited: Revised criteria for the diagnosis of amyotrophic lateral sclerosis

Benjamin Rix Brooks, Robert G. Miller, Michael Swash, Theodore L. Munsat

S4210235782. 20005,440 Citations

Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS

Mariely DeJesus‐Hernandez, Ian R. Mackenzie, Bradley F. Boeve, Adam L. Boxer, Matt Baker, Nicola J. Rutherford, Alexandra M. Nicholson, NiCole A. Finch, Heather C. Flynn, Jennifer Adamson, Naomi Kouri, Aleksandra Wojtas, Pheth Sengdy, Ging‐Yuek Robin Hsiung, Anna Karydas, William W. Seeley, Keith A. Josephs, Giovanni Coppola, Daniel H. Geschwind, Zbigniew K. Wszołek, Howard Feldman, David S. Knopman, Ronald C. Petersen, Bruce L. Miller, Dennis W. Dickson, Khrista Boylan, Neill R. Graff‐Radford, Rosa Rademakers

Neuron. 20115,010 CitationsOPEN ACCESS

A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD

Alan E. Renton, Elisa Majounie, Adrian J. Waite, Javier Simón‐Sánchez, Sara Rollinson, J. Raphael Gibbs, Jennifer C. Schymick, Hannu Laaksovirta, John C. van Swieten, Liisa Myllykangas, Hannu Kalimo, Anders Paetau, Yevgeniya Abramzon, Anne M. Remes, Alice Kaganovich, Sonja W. Scholz, Jamie Duckworth, Jinhui Ding, Daniel W. Harmer, Dena G. Hernandez, Janel O. Johnson, Kin Y. Mok, Mina Ryten, Daniah Trabzuni, Rita Guerreiro, Richard W. Orrell, James Neal, Alex Murray, Justin Pearson, Iris E. Jansen, David Sondervan, Harro Seelaar, Derek J. Blake, Kate Young, Nicola Halliwell, Janis Bennion Callister, Greg Toulson, Anna Richardson, Alexander Gerhard, Julie S. Snowden, David Mann, David Neary, Michael A. Nalls, Terhi Peuralinna, Lilja Jansson, Veli‐Matti Isoviita, Anna-Lotta Kaivorinne, Maarit Hölttä‐Vuori, Elina Ikonen, Raimo Sulkava, Michael Benatar, Joanne Wuu, Adriano Chiò, Gabriella Restagno, Giuseppe Borghero, Mario Sabatelli, David Heckerman, Ekaterina Rogaeva, Lorne Zinman, Jeffrey D. Rothstein, Michael Sendtner, Carsten Drepper, Evan E. Eichler, Can Alkan, Ziedulla Abdullaev, Svetlana Pack, Amalia Dutra, Evgenia Pak, John Hardy, Andrew Singleton, Nigel Williams, Peter Heutink, Stuart Pickering‐Brown, Huw R. Morris, Pentti J. Tienari, Bryan J. Traynor

Neuron. 20114,500 CitationsOPEN ACCESS