Cancer Mechanisms and Therapy

TopicLeading institutions, researchers & key papers

This cluster of papers focuses on the role of Pim oncogenes, particularly Pim-1 and Pim-2 kinases, in promoting tumorigenesis, cancer progression, and metastasis. The cluster also explores the potential of targeting Pim kinases as a therapeutic approach, with a specific emphasis on their involvement in cell survival pathways, phosphorylation of key proteins, and their association with hematological malignancies.

179

Works

IDs:OpenAlex

How has Cancer Mechanisms and Therapy's publication output changed over time?

ScholarIQpublication output · 1997–2021

Output grew100% over the shown period — from 1 works in 1997 to 2 in 2021.

1997200320102012201320142015201820202021

What are the most-cited papers on Cancer Mechanisms and Therapy?

ScholarIQmost cited works

EGFR activation limits the response of liver cancer to lenvatinib

Haojie Jin, Yao Shi, Yuanyuan Lv, Shengxian Yuan, Christel Ramirez, Cor Lieftink, Liqin Wang, Siying Wang, Cun Wang, Matheus Henrique Dias, Fleur Jochems, Yuan Yang, Astrid Bosma, E. Marielle Hijmans, Marnix H. P. de Groot, Serena Vegna, Dan Cui, Yangyang Zhou, Ling Jing, Hui Wang, Yuchen Guo, Xingling Zheng, Nikita Isima, Hai-Qiu Wu, Chong Sun, Roderick L. Beijersbergen, Leila Akkari, Weiping Zhou, Bo Zhai, Wenxin Qin, René Bernards

Nature. 2021440 Citations

Direct Interaction of the Rho GDP Dissociation Inhibitor with Ezrin/Radixin/Moesin Initiates the Activation of the Rho Small G Protein

Kazuo Takahashi, Takuya Sasaki, Akiko Mammoto, Kenji Takaishi, Takaaki Kameyama, Sachiko Tsukita, Shöichiro Tsukita, Yoshimi Takai

S140251998. 1997429 CitationsOPEN ACCESS

Exome sequencing of hepatitis B virus–associated hepatocellular carcinoma

Jian Huang, Qing Deng, Qun Wang, Kun Yu Li, Ji Hong Dai, Li Niu, Zhi Dong Zhu, Bo Zhou, Xiao Yan Liu, Rui Fang Liu, Qian Lan Fei, Hui Chen, Bing Cai, Boping Zhou, Hua-Sheng Xiao, Lun Qin, Ze‐Guang Han

S137905309. 2012393 Citations

Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations

Masao Mizuki, Joachim Schwäble, Claudia Steur, Chunaram Choudhary, Shuchi Agrawal, Bülent Sargin, Björn Steffen, Itaru Matsumura, Yuzuru Kanakura, Frank D. Böhmer, Carsten Müller‐Tidow, Wolfgang E. Berdel, Hubert Serve

Blood. 2003298 CitationsOPEN ACCESS

LINC01638 lncRNA activates MTDH-Twist1 signaling by preventing SPOP-mediated c-Myc degradation in triple-negative breast cancer

Liyun Luo, Hailin Tang, Ling Li, Nan Li, Xiaoting Jia, Zhijie Zhang, Xiaorong Wang, Lejuan Shi, Jiang Yin, Ni Qiu, Hao Liu, Ying Song, Kai Luo, Hongsheng Li, Zhimin He, Guopei Zheng, Xiaoming Xie

S128439998. 2018151 Citations