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Cell death mechanisms and regulation
TopicLeading institutions, researchers & key papers
This cluster of papers explores the molecular mechanisms, regulation, and implications of apoptosis and other forms of cell death, with a focus on the roles of Bcl-2 family proteins, mitochondria, TNF signaling, caspases, and reactive oxygen species. It also delves into the application of these insights in cancer therapy.
217
Works
IDs:OpenAlex
How has Cell death mechanisms and regulation's publication output changed over time?
ScholarIQpublication output · 1998–2017
Output declined67% over the shown period — from 3 works in 1998 to 1 in 2017.
3
1
2
1
1
1
2
1
1
1
1998199920002007201120132014201520162017
What are the most-cited papers on Cell death mechanisms and regulation?
ScholarIQmost cited works
Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis
Honglin Li, Hong Zhu, Chi-jie Xu, Junying Yuan
S110447773. 19984,445 CitationsOPEN ACCESS
Molecular characterization of mitochondrial apoptosis-inducing factor
Santos A. Susín, Hans Kristian Lorenzo, Naoufal Zamzami, Isabel Marzo, Bryan E. Snow, Greg M. Brothers, Joan Mangion, Étienne Jacotot, Paola Costantini, Markus Loeffler, Nathanaël Larochette, David R. Goodlett, Ruedi Aebersold, David P. Siderovski, Josef Penninger, Guido Kroemer
Nature. 19994,059 Citations
Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis
Claudia Günther, Eva Martini, Nadine Wittkopf, Kerstin Amann, Benno Weigmann, Helmut Neumann, Maximilian J. Waldner, Stephen Μ. Hedrick, Stefan Tenzer, Markus F. Neurath, Christoph Becker
Nature. 2011887 Citations
Murine Caspase-11, an ICE-Interacting Protease, Is Essential for the Activation of ICE
Suyue Wang, Masayuki Miura, Yong‐Keun Jung, Hong Zhu, En Li, Junying Yuan
S110447773. 1998701 CitationsOPEN ACCESS
Where is Cell death mechanisms and regulation research published, and who funds it?
ScholarIQvenues & funding sources
TOP JOURNALS
TOP FUNDERS
National Science Foundation—
NIH—
Wellcome Trust—
European Research Council—
Funder breakdown is a member featureSign up free to unlock
How much of the research on Cell death mechanisms and regulation is open access?
ScholarIQopen access share
80%OPEN ACCESS
Gold
13%
Green
20%
Hybrid
13%
Bronze
33%
Closed
20%
Related on ScholarIQ
Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked
Paper
Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis
Paper
Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
Paper
Molecular characterization of mitochondrial apoptosis-inducing factor
Paper
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β
Paper
Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death
Paper