Chemical Reactions and Isotopes

TopicLeading institutions, researchers & key papers

This cluster of papers focuses on the use of deuterium and tritium labeling, hydrogen isotope exchange, and catalysis in drug discovery and development. It explores applications in medicinal chemistry, metabolism studies, and the incorporation of deuterium into pharmaceutical compounds. The research also highlights the use of iridium-catalyzed reactions and the impact of deuterium substitution on drug pharmacokinetics.

Works

IDs:OpenAlex

How has Chemical Reactions and Isotopes's publication output changed over time?

ScholarIQpublication output · 1974–2022

Output grew0% over the shown period — from 1 works in 1974 to 1 in 2022.

1974197819962003200920162022

What are the most-cited papers on Chemical Reactions and Isotopes?

ScholarIQmost cited works

Effect of Deutetrabenazine on Chorea Among Patients With Huntington Disease

Huntington Study Group, Samuel Frank, Claudia Testa, David Stamler, Elise Kayson, Charles S. Davis, Mary Edmondson, Shari Kinel, Blair R. Leavitt, David Oakes, Christine J. O’Neill, Christina Vaughan, Jody Goldstein, Margaret Herzog, Victoria Snively, Jacquelyn Whaley, Cynthia Wong, Greg Suter, Joseph Jankovic, Joohi Jimenez‐Shahed, Christine Hunter, Daniel O. Claassen, Olivia C. Roman, Victor Sung, Jenna Smith, Sarah Janicki, Ronda Clouse, Marie Saint‐Hilaire, Anna DePold Hohler, Denyse Turpin, Raymond James, Ramon L. Rodriguez, Kyle Rizer, Karen E. Anderson, Hope Heller, Alexis Carlson, Susan R. Criswell, Brad A. Racette, Fredy J. Revilla, Frederick C. Nucifora, Russell L. Margolis, MaryJane Ong, Tilak Mendis, Neila Mendis, Carlos Singer, Mónica Quesada, Jane S. Paulsen, Thomas Brashers-Krug, Amanda C. Miller, Jane Kerr, Richard Dubinsky, Carolyn Steele Gray, Stewart A. Factor, Elaine Sperin, Eric Molho, Mary Eglow, Sharon Evans, Rajeev Kumar, Christina Reeves, Ali Samii, Sylvain Chouinard, Monica Beland, B.L. Scott, Patrick Hickey, Sherali Esmail, Wai Lun Alan Fung, Clare Gibbons, Lina Qi, Amy Colcher, Cory Hackmyer, Andrew McGarry, Kevin J. Klos, Mark Gudesblatt, Lori Fafard, Laura Graffitti, Daniel Schneider, Rohit Dhall, Joanne Wojcieszek, Kathrin LaFaver, Andrew P. Duker, Erin Neefus, Hilary Wilson, David Shprecher, Paola Wall, Karen Blindauer, Lynn Wheeler, James T. Boyd, Emily Houston, Eric S. Farbman, Pinky Agarwal, Shirley Eberly, Arthur Watts, Pierre N. Tariot, Andrew Feigin, Scott Evans, Chris Beck, Constance Orme, Jon Edicola, Emily Christopher

JAMA. 2016401 CitationsOPEN ACCESS

Results of Long-Term Iron-Chelating Therapy

V. Gabutti, Antonio Piga

S182948766. 2009382 Citations

Cholestyramine: Use as a New Therapeutic Approach for Chlordecone (Kepone) Poisoning

James J. Boylan, John L. Egle, Philip S. Guzelian

Science. 197891 Citations

Cytochrome P450 metabolic dealkylation of nine N-nitrosodialkylamines by human livermicrosomes

Gwénaëlle Bellec, Yvonne Dréano, P Lozac’h, J.F. Ménez, F. Berthou

S184620562. 199674 Citations

Enzymatic Dehydrogenation of Testosterone Coupled to Pyruvate Reduction in a Two-Phase System

Pietro Cremonesi, Giacomo Carrea, Luigi Ferrara, Eraldo Antonini