Endoplasmic Reticulum Stress and Disease

TopicLeading institutions, researchers & key papers

This cluster of papers focuses on the molecular mechanisms, regulation, and consequences of endoplasmic reticulum (ER) stress and the unfolded protein response (UPR). It explores the role of ER stress in various diseases such as diabetes, cancer, neurodegenerative diseases, and liver disease, highlighting its impact on cell fate decisions, protein folding, oxidative stress, and apoptosis. The cluster also delves into the involvement of UPR pathways, chaperones, and the interplay between ER stress and inflammation.

242

Works

IDs:OpenAlex

How has Endoplasmic Reticulum Stress and Disease's publication output changed over time?

ScholarIQpublication output · 2000–2015

Output declined67% over the shown period — from 3 works in 2000 to 1 in 2015.

20002004200520072009201020122015

What are the most-cited papers on Endoplasmic Reticulum Stress and Disease?

ScholarIQmost cited works

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β

Toshiyuki Nakagawa, Hong Zhu, Nobuhiro Morishima, En Li, Jin Xu, Bruce A. Yankner, Junying Yuan

Nature. 20003,268 Citations

TRB3, a novel ER stress‐inducible gene, is induced via ATF4–CHOP pathway and is involved in cell death

Nobumichi Ohoka, Satoshi Yoshii, Takayuki Hattori, Kikuo Onozaki, Hidetoshi Hayashi

S127916151. 20051,040 CitationsOPEN ACCESS

Calreticulin, a multi-process calcium-buffering chaperone of the endoplasmic reticulum

Marek Michalak, Jody Groenendyk, Éva Szabó, Leslie I. Gold, Michał Opas

S44425019. 2009715 Citations

ER stress‐regulated translation increases tolerance to extreme hypoxia and promotes tumor growth

Meixia Bi, Christine Naczki, Marianne Koritzinsky, Diane Fels, Jaime D. Blais, Nianping Hu, Heather P. Harding, Isabelle Novoa, Mahesh A. Varia, James A. Raleigh, Donalyn Scheuner, Randal J. Kaufman, John C. Bell, David Ron, Bradly G. Wouters, Constantinos Koumenis

S127916151. 2005711 CitationsOPEN ACCESS

Prolonged Endoplasmic Reticulum Stress in Hypertrophic and Failing Heart After Aortic Constriction

Kenichiro Okada, Tetsuo Minamino, Yoshitane Tsukamoto, Yulin Liao, Osamu Tsukamoto, Seiji Takashima, Akio Hirata, Masashi Fujita, Y. Nagamachi, Takeshi Nakatani, Chikao Yutani, Kentaro Ozawa, Satoshi Ogawa, Hitonobu Tomoike, Masatsugu Hori, Masafumi Kitakaze

Circulation. 2004526 CitationsOPEN ACCESS