Epigenetics and DNA Methylation

TopicLeading institutions, researchers & key papers

This cluster of papers explores the diverse mechanisms and functional implications of epigenetic modifications, including DNA methylation, histone modification, and chromatin remodeling. It delves into the role of these modifications in various biological processes such as cancer development, transgenerational inheritance, and environmental responses. Additionally, it discusses the potential applications of epigenetic therapy.

798

Works

IDs:OpenAlex

How has Epigenetics and DNA Methylation's publication output changed over time?

ScholarIQpublication output · 1995–2018

Output declined50% over the shown period — from 2 works in 1995 to 1 in 2018.

1995200020082009201020112012201520162018

What are the most-cited papers on Epigenetics and DNA Methylation?

ScholarIQmost cited works

Persistent epigenetic differences associated with prenatal exposure to famine in humans

Bastiaan T. Heijmans, Elmar W. Tobi, Aryeh D. Stein, Hein Putter, Gerard J. Blauw, Ezra Susser, P. Eline Slagboom, L. H. Lumey

Proceedings of the National Academy of Sciences. 20083,063 CitationsOPEN ACCESS

Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma

Houtan Noushmehr, Daniel J. Weisenberger, Kristin Diefes, Heidi Phillips, Kanan Pujara, Benjamin P. Berman, Fei Pan, Christopher E. Pelloski, Erik P. Sulman, Krishna Bhat, Roel G.W. Verhaak, Katherine A. Hoadley, D. Neil Hayes, Charles M. Perou, Heather K. Schmidt, Li Ding, Richard K. Wilson, David Van Den Berg, Hui Shen, Henrik Bengtsson, Pierre Neuvial, Leslie Cope, Jonathan D. Buckley, James G. Herman, Stephen B. Baylin, Peter W. Laird, Kenneth Aldape

S25671836. 20102,370 CitationsOPEN ACCESS

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

Arun Sreekumar, Laila Poisson, Thekkelnaycke M. Rajendiran, Amjad Khan, Qi Cao, Jindan Yu, Bharathi Laxman, Rohit Mehra, Robert J. Lonigro, Yong Li, Mukesh K. Nyati, Aarif Ahsan, Shanker Kalyana‐Sundaram, Bo Han, Xuhong Cao, Jaeman Byun, Gilbert S. Omenn, Debashis Ghosh, Subramaniam Pennathur, Danny C. Alexander, Alvin Berger, Jeffrey R. Shuster, John T. Wei, Sooryanarayana Varambally, Chris Beecher, Arul M. Chinnaiyan

Nature. 20092,260 CitationsOPEN ACCESS

5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

Adrian Merlo, James G. Herman, Li Mao, Daniel J. Lee, Edward Gabrielson, Peter C. Burger, Stephen B. Baylin, David Sidransky

Nature Medicine. 19951,993 Citations

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

Richard Possemato, Kevin M. Marks, Yoav D. Shaul, Michael E. Pacold, Dohoon Kim, Kıvanç Birsoy, Shalini Sethumadhavan, Hin-Koon Woo, Hyun Gyung Jang, Abhishek Jha, Walter W. Chen, Francesca G. Barrett, Nicolas Stransky, Zhi-Yang Tsun, Glenn S. Cowley, Jordi Barretina, Nada Y. Kalaany, Peggy P. Hsu, Kathleen Ottina, A. M. C. Chan, Bingbing Yuan, Levi A. Garraway, David E. Root, Mari Mino–Kenudson, Elena F. Brachtel, Edward M. Driggers, David M. Sabatini

Nature. 20111,735 CitationsOPEN ACCESS