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Inflammatory mediators and NSAID effects
TopicLeading institutions, researchers & key papers
This cluster of papers focuses on the use of cyclooxygenase-2 (COX-2) inhibitors, such as rofecoxib, celecoxib, and naproxen, in the context of inflammation and cancer. It explores the gastrointestinal and cardiovascular toxicity, chemopreventive effects, and potential risks associated with these drugs. The cluster also delves into the molecular biology of prostaglandins, particularly prostaglandin E2, and their role in modulating immune responses and promoting cancer growth.
241
Works
IDs:OpenAlex
How has Inflammatory mediators and NSAID effects's publication output changed over time?
ScholarIQpublication output · 1993–2011
Output declined50% over the shown period — from 2 works in 1993 to 1 in 2011.
2
1
1
2
1
2
1
1
1
1
1993199419981999200020012003200420082011
What are the most-cited papers on Inflammatory mediators and NSAID effects?
ScholarIQmost cited works
Comparison of Upper Gastrointestinal Toxicity of Rofecoxib and Naproxen in Patients with Rheumatoid Arthritis
Claire Bombardier, Loren Laine, Alise Reicin, Deborah R. Shapiro, Rubén Burgos‐Vargas, Barry R. Davis, Richard O. Day, Marcos Bosi Ferraz, Christopher J. Hawkey, Marc C. Hochberg, Tore K Kvien, Thomas J. Schnitzer
New England Journal of Medicine. 20004,044 CitationsOPEN ACCESS
Prostaglandins and Inflammation
Emanuela Ricciotti, Garret A. FitzGerald
S3485792. 20113,787 CitationsOPEN ACCESS
Cyclooxygenase in biology and disease
Raymond N. DuBois, Steven B. Abramson, Leslie J. Crofford, Rajnish A. Gupta, Lee S. Simon, L. B. A. van de Putte, Peter E. Lipsky
The FASEB Journal. 19982,508 Citations
Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase.
Jane A. Mitchell, Pravit Akarasereenont, Christoph Thiemermann, R.J. Flower, John R. Vane
Proceedings of the National Academy of Sciences. 19931,669 CitationsOPEN ACCESS
The Coxibs, Selective Inhibitors of Cyclooxygenase-2
Garret A. FitzGerald, Carlo Patrono
New England Journal of Medicine. 20011,569 Citations
Where is Inflammatory mediators and NSAID effects research published, and who funds it?
ScholarIQvenues & funding sources
TOP JOURNALS
TOP FUNDERS
National Science Foundation—
NIH—
Wellcome Trust—
European Research Council—
Funder breakdown is a member featureSign up free to unlock
How much of the research on Inflammatory mediators and NSAID effects is open access?
ScholarIQopen access share
53%OPEN ACCESS
Gold
0%
Green
13%
Hybrid
0%
Bronze
40%
Closed
47%
Related on ScholarIQ
Comparison of Upper Gastrointestinal Toxicity of Rofecoxib and Naproxen in Patients with Rheumatoid Arthritis
Paper
Prostaglandins and Inflammation
Paper
Cyclooxygenase in biology and disease
Paper
A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism.
Paper
Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase.
Paper
The Coxibs, Selective Inhibitors of Cyclooxygenase-2
Paper